Beta Agonists

Beta Agonists Mode of Action Inhaled short-acting β-agonists produce immediate bronchodilation lasting 4-6 hours. These drugs stimulate β2 receptors present in airway smooth muscle, increasing levels of intracellular cyclic AMP, which in turn activates protein kinase A (PKA). PKA phosphorylates several proteins to reduce intracellular Ca2+ levels and promote smooth muscle relaxation. This action is […]
Inhaled Corticosteroids

Inhaled Corticosteroids Mode of Action Corticosteroids bind to cytosolic glucocorticoid receptors to decrease transcription and production of inflammatory cytokines e.g. interleukin (IL)-4 (IL-4), IL-13, granulocyte macrophage colony stimulating factor (GM-CSF), eotaxin and regulated on activation, normal T cells expressed and secreted (RANTES), which function in bronchoconstriction and airway inflammation.Corticosteroids suppress eosinophilic airway inflammation in asthma. […]
Pulmonary Function Test

Pulmonary Function Test Spirometry is the only objective method to diagnose Obstructive Airways Diseases (Asthma and COPD). It also helps in monitoring the treatment.Most the doctors diagnose Asthma only by obtaining a history and listening to lung sounds with a stethoscope. However, with this approach, 65% of patients suffering from obstructive airway disease remain undetected. […]
Pathology

Pathology All diagnostic pathology services are available under one roof, in the clinic. We perform all tests in biochemistry, hematology, microbiology, clinical pathology, serology, and histopathology and also have various test profiles for all diseases. edit post Who can be tested for allergies? Read More edit post Drug Allergy Read More edit post Allergic Conjunctivitis […]
Peak Flow Monitoring

Peak Flow Monitoring PEAK FLOW MONITORING A peak flow meter is a device that measures how well air moves out of the lungs. A peak flow meter is used to manage exacerbations. A peak flow meter is used for daily long-term monitoring. A peak flow meter guides therapeutic decisions in the home, school, clinician’s office, […]
Autologous Serum Skin Test

Autologous Serum Skin Test Autologous Serum Skin TestAsst test is performed by your doctor in the clinic; patient’s venous blood was placed in sterile plastic tubes and allowed to clot at room temperature for 30 minutes. Then the serum was separated by centrifugation at 500 x g for 15 minutes and kept in aliquots for […]
Patch Test

Patch Test A patch test is used to find allergic causes of eczema/dermatitis and some other types of skin reactions such as reactions to drugs.You may advise a patch test:The tests can diagnose lung diseases, measure the severity of lung problems, and check to see how well treatment for a lung disease is working. If […]
Allergy Blood Test

Allergy Blood Test Allergy Blood Test Blood tests measure the amount of IgE antibody circulating in the blood. The test is carried out on a small sample of blood, usually taken from a vein in the arm in the usual way. The sample is then sent to a laboratory and the results are available in […]
Allergy Skin Testing

Allergy Skin Testing Allergy test plays a pivotal role in Allergy diagnosis and treatment. Allergy Tests are used to confirm clinical sensitivity induced by aeroallergens, foods, some drugs, a few chemicals, and Hymenoptera venom. Vaccines Highly recommended for Asthmatics An allergy test can be broadly divided into two groups- 1 Allergy Blood test 2 Allergy […]
Anaphylaxis

Anaphylaxis Anaphylaxis is serious, potentially life threatening allergic reaction. It can occur within seconds or minutes of exposure to something you’re allergic to, such as insect bites, foods, and medications. Symptoms generalised flushing of the skin nettle rash (hives) anywhere on the body sense of impending doom swelling of throat and mouth difficulty in swallowing […]